Novel Tissue Nanotransfection to Help Replacement of Damaged Organ and Tissues

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Tissue Nanotransfection

In a recent study conducted at the Ohio State University, scientists have claimed to have invented a novel microchip technology that will help in replacing damaged or injured organs or tissues and facilitate the healing of wounds and nerves. The technology, considered a breakthrough, is reckoned as Tissue Nanotransfection (TNT) that uses a small microchip to turn skin cells into a variety of other types of cell, specialized for repairing damaged tissues. The research was published in the journal Nature Nanotechnology.

In a series of experiments conducted on mice and pigs, scientists injected the miniature chip on their cells, and after a week observed the formation of new blood vessels and nerve tissues. Tissue Nanotransfection (TNT) functions by injecting genetic code into body’s cells and starts working in fraction of a second, triggering the reprogramming of cells. In one of the experiments, they showed how they injected a chip to trigger new nerve cell formations in a mouse’s brain so that it could recover from a stroke.

Success of Nanotechnology in Humans Could Help in Treating Parkinson’s disease and Alzheimer’s

The technology is still to be tested on human skin, expectedly in next year. This may prove immensely helpful in discovering therapies for patients with Parkinson’s disease, Alzheimer’s, strokes, and nerve damages.

The scientists contended that the Tissue Nanotransfection (TNT) technology is largely non-invasive and only needs a light-intensity electric current making the process virtually pain-free. According to one of the researchers, this is the first time they have conducted a study in which the cell programming is possible within the body of organisms. This is significant since the process can be effected outside laboratory in hospitals and general process surgeries. An additional benefit of the new process is that it does away with the use of immunosuppressant drugs. This is required in several cases in order to minimize the risk of rejection by the patients’ immune system.

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